Molecular genetic influences on attentional control and other executive processes and their links with psychopathology in the AFFECT study

Justin D. Tubbs, T. Mallard, Maria Dalby, Yunxuan Jiang, Y. Lee, Karmel W Choi, Tian Ge, Niels Plath, L. Hammer-Helmich, J. Granka, A. Grotzinger, David Hinds, Jordan W Smoller, Joshua W. Buckholtz

medRxiv, 2025

Towards Scalable Biomarker Discovery in Posttraumatic Stress Disorder: Triangulating Genomic and Phenotypic Evidence from a Health System Biobank

Y. Lee, Yingzhe Zhang, Ana Lucia Espinosa Dice, Josephine H. Li, J. Tubbs, Yen-Chen Anne Feng, Tian Ge, A. Maihofer, C. Nievergelt, J. Smoller, K. Koenen, Andrea L. Roberts, Natalie Slopen

medRxiv, 2025

Uncovering Genetic Risk Beyond Diagnoses in Suicidal Thoughts and Behaviors: Insights from All of Us

Phil H Lee, Brandon T. Sanzo, Y. Lee, Daniel H. Jung, Jodi M. Gilman, Matthew K. Nock, J. Smoller, Richard T. Liu, Ronald C Kessler

medRxiv, 2025

Enhancing Suicide Risk Prediction With Polygenic Scores in Psychiatric Emergency Settings: Prospective Study

Y. Lee, Yingzhe Zhang, Chris J Kennedy, T. Mallard, Zhaowen Liu, Phuong Linh Vu, Yen-Chen Anne Feng, Tian Ge, M. Petukhova, Ronald C. Kessler, M. Nock, J. Smoller

JMIR Bioinformatics and Biotechnology, 2024

Examining the Genetic Links between Clusters of Immune-mediated Diseases and Psychiatric Disorders

S. Breunig, Y. Lee, Elizabeth Karlson, Arjun Krishnan, J. M. Lawrence, L. S. Schaffer, A. Grotzinger

medRxiv, 2024

Genetic architecture and socio-environmental risk factors for major depressive disorder in Nepal.

Karmel W Choi, J. Tubbs, Y. Lee, Yixuan He, K. Tsuo, Mary T Yohannes, Lethukuthula L Nkambule, Emily M. Madsen, Dirgha J. Ghimire, Sabrina Hermosilla, Tian Ge, Alicia R. Martin, W. Axinn, Jordan W Smoller

Psychological Medicine, 2024

Impact of Participation Bias on Disease Prevalence Estimation in the All of Us Research Program: A Case Study of Ischemic Heart Disease and Stroke

Y. Lee, Ankita Patil, Cheryl R. Clark, Monik, C. Botero, David W. Stein, Elizabeth Karlson

medRxiv, 2024

W20. IMMUNE MARKERS MEDIATE THE GENETIC RELATIONSHIPS BETWEEN IMMUNE DISEASES AND PSYCHIATRIC DISORDERS

Sophie Breunig, Y. Lee, Elizabeth Karlson, A. Grotzinger

European Neuropsychopharmacology, 2024

W98. GENETIC ARCHITECTURE AND POLYGENIC PREDICTION OF ALCOHOL USE DISORDER IN NEPAL

Yixuan He, J. Tubbs, Karmel Choi, K. Tsuo, Tian Ge, Y. Lee, Jordan W Smoller, William Axinn, Alicia Martin

European Neuropsychopharmacology, 2024

Characterizing the phenotypic and genetic structure of psychopathology in UK Biobank

C. Williams, Hugo Peyre, Tobias Wolfram, Y. Lee, Tian Ge, J. Smoller, T. Mallard, F. Ramus

medRxiv, 2023

Determining Distinct Suicide Attempts From Recurrent Electronic Health Record Codes: Classification Study

Kate H Bentley, Emily M. Madsen, Eugene Song, Yu Zhou, Victor M Castro, Hyunjoon Lee, Y. Lee, J. Smoller

JMIR Formative Research, 2023

Genetic Heterogeneity Across Dimensions of Alcohol Use Behaviors

Jeanne E Savage, P. Barr, Tanya Phung, Y. Lee, Yingzhe Zhang, V. McCutcheon, Tian Ge, J. Smoller, Lea K. Davis, Jacquelyn Meyers, B. Porjesz, D. Posthuma, T. Mallard, S. Sanchez-Roige

medRxiv, 2023

Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory Outcomes.

G. Pathak, Kritika Singh, Karmel W Choi, Yu Fang, Manuela R Kouakou, Y. Lee, Xiang Zhou, L. Fritsche, Frank R Wendt, Lea K. Davis, R. Polimanti

JAMA psychiatry, 2023

Social support and depression during a global crisis

Karmel W. Choi, Y. Lee, Zhaowen Liu, D. Fatori, J. Bauermeister, Rebecca A Luh, Cheryl R. Clark, A. R. Brunoni, S. Bauermeister, J. Smoller

Nature Mental Health, 2023

T38. CHARACTERIZING THE PHENOTYPIC AND GENETIC STRUCTURE OF PSYCHOPATHOLOGY IN UK BIOBANK

C. Williams, Hugo Peyre, Tobias Wolfram, Y. Lee, Tian Ge, Jordan W Smoller, T. Mallard, F. Ramus

European Neuropsychopharmacology, 2023

Association of Everyday Discrimination With Depressive Symptoms and Suicidal Ideation During the COVID-19 Pandemic in the All of Us Research Program.

Younga H. Lee, Zhaowen Liu, D. Fatori, J. Bauermeister, Rebecca A Luh, Cheryl R. Clark, S. Bauermeister, A. Brunoni, J. Smoller

JAMA psychiatry, 2022

Community-Level Social Support Infrastructure and Adult Onset of Major Depressive Disorder in a South Asian Postconflict Setting.

W. Axinn, Karmel W. Choi, D. Ghimire, Faith Cole, S. Hermosilla, C. Benjet, Melany C Morgenstern, Younga H. Lee, J. Smoller

JAMA psychiatry, 2022

Effects of social support on depression risk during the COVID-19 pandemic: What support types and for whom?

Karmel W. Choi, Y. Lee, Zhaowen Liu, D. Fatori, J. Bauermeister, Rebecca A Luh, C. Clark, A. Brunoni, S. Bauermeister, J. Smoller

medRxiv, 2022

Impact of selection bias on polygenic risk score estimates in healthcare settings

Y. Lee, Tanayott Thaweethai, Y. Sheu, Y. Feng, E. Karlson, T. Ge, P. Kraft, J. Smoller

Psychological Medicine, 2022

Infections During Pregnancy and Risks for Adult Psychosis: Findings from the New England Family Study.

S. Buka, Y. Lee, J. Goldstein

Current topics in behavioral neurosciences, 2022

POLYGENIC SCORE OF POST-TRAUMATIC STRESS DISORDER HIGHLIGHTS ASSOCIATION WITH CARDIOVASCULAR DISORDERS IN ELECTRONIC HEALTH RECORDS OF >94,000 INDIVIDUALS

G. Pathak, Kritika Singh, Karmel W. Choi, Shea J Andrew, B. Fulton-Howard, Y. Lee, L. Davis, R. Polimanti

European Neuropsychopharmacology, 2022

The molecular genetic landscape of human brain size variation

J. Seidlitz, T. Mallard, Jacob W. Vogel, Y. Lee, V. Warrier, Gareth Ball, O. Hansson, L. Hernandez, Ayan S. Mandal, K. Wagstyl, M. Lombardo, E. Courchesne, J. Glessner, T. Satterthwaite, R. Bethlehem, J. Bernstock, S. Tasaki, B. Ng, Chris Gaiteri, J. Smoller, T. Ge, R. Gur, M. Gandal, A. Alexander-Bloch

bioRxiv, 2022

Trajectories of common mental disorders symptoms before and during the COVID-19 pandemic: findings from the ELSA-Brasil COVID-19 Mental Health Cohort

D. Fatori, Paulo J C Suen, Pedro Bacchi, Leonardo Afonso, Izio Klein, B. Cavendish, Y. Lee, Zhaowen Liu, J. Bauermeister, Marina L. Moreno, Maria Carmen Viana, A. Goulart, I. Santos, S. Bauermeister, J. Smoller, P. Lotufo, I. Benseñor, A. Brunoni

Social Psychiatry and Psychiatric Epidemiology, 2022

76. IMPACT OF ASCERTAINMENT BIAS ON POLYGENIC RISK SCORE ESTIMATES IN HEALTHCARE SETTINGS

Younga H. Lee, T. Thaweethai, Y. Sheu, Y. Feng, T. Ge, P. Kraft, J. Smoller

European Neuropsychopharmacology, 2021

Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease

J. Dennis, J. Sealock, P. Straub, Younga H. Lee, D. Hucks, K. Actkins, A. Faucon, Y. Feng, T. Ge, S. Goleva, M. Niarchou, Kritika Singh, T. Morley, J. Smoller, D. Ruderfer, J. Mosley, Guanhua Chen, L. Davis

Genome medicine, 2021

Use of the PsycheMERGE Network to Investigate the Association Between Depression Polygenic Scores and White Blood Cell Count

J. Sealock, Younga H. Lee, A. Moscati, S. Venkatesh, G. Voloudakis, P. Straub, Kritika Singh, Y. Feng, T. Ge, P. Roussos, J. Smoller, Guanhua Chen, L. Davis

JAMA psychiatry, 2021

Feasibility of Using a Nationally Representative Telephone Survey to Monitor Multiple Sclerosis Prevalence in the United States

S. Buka, M. Wallin, W. Culpepper, Younga H. Lee, R. Marrie, L. Nelson, W. Kaye, L. Wagner, H. Tremlett, Jon Campbell, N. Larocca

Neuroepidemiology, 2020

Increased depression genetic liability associates with inflammatory markers in multiple electronic health record systems

L. Davis, J. Sealock, Younga H. Lee, A. Moscati, S. Venkatesh, G. Voloudakis, P. Straub, Kritika Singh, Y. Feng, T. Ge, P. Roussos, J. Smoller, Guanhua Chen

2020

Effects of prenatal bacterial infection on cognitive performance in early childhood.

Younga H. Lee, G. Papandonatos, D. Savitz, W. Heindel, S. Buka

Paediatric and perinatal epidemiology, 2019

Maternal Bacterial Infection During Pregnancy and Offspring Risk of Psychotic Disorders: Variation by Severity of Infection and Offspring Sex.

Younga H. Lee, S. Cherkerzian, L. Seidman, G. Papandonatos, D. Savitz, M. Tsuang, J. Goldstein, S. Buka

The American journal of psychiatry, 2019